Journal
TISSUE ANTIGENS
Volume 65, Issue 1, Pages 120-122Publisher
WILEY
DOI: 10.1111/j.1399-0039.2005.00339.x
Keywords
DPA1; DPA1*010303; DPA1*0303; SBT; TBSA
Categories
Funding
- PHS HHS [R01 A1 49383] Funding Source: Medline
Ask authors/readers for more resources
We report here two novel DPA1 alleles, DPA1*010303 and DPA1*0303, identified from a Kenyan population during sequence-based HLA-DPA1 typing. Molecular cloning and sequencing of multiple clones confirmed that one of the new DPA1 alleles is identical to DPA1*010301 at exon 2, except for a single nucleotide substitution (ACG ACC) at codon 15. The new allele has been named by the WHO Nomenclature Committee as DPA1*010303. The second novel DPA1 allele is identical to DPA1*0301, except for a single nucleotide difference (GAA GAC) at codon 28 that changed the amino acid from Glu to Asp. The new allele has been named by the WHO Nomenclature Committee as DPA1*0303. Identification of the two novel DPA1 alleles reflects the genetic diversity of this East African population.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available