4.6 Article

Prebiotic carbohydrate synthesis: zinc-proline catalyzes direct aqueous aldol reactions of alpha-hydroxy aldehydes and ketones

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 3, Issue 10, Pages 1850-1855

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b501512j

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Zn-proline catalyzed aldolisation of glycoladehyde gave mainly tetroses whereas in the cross-aldolisation of glycoladehyde and rac-glyceraldehyde, pentoses accounted for 60% of the sugars formed with 20% of ribose.

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