Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 3, Issue 17, Pages 3102-3104Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b507156a
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Selective inhibitors of type II dehydroquinase were rationally designed to explore a second binding-pocket in the active-site. The molecular modelling, synthesis, inhibition studies and crystal structure determination are described.
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