Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 3, Issue 17, Pages 3094-3095Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b508464d
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Palladium catalysed C-N bond formation can be used to convert vinyl bromides to the corresponding enamines, which are reacted in situ with alkylidene malonates to provide Michael adducts. The overall transformation results in cine-substitution of the starting vinyl bromide.
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