A new triterpenoid ester from the fruits of Bruguiera parviflora

A new lupane caffeoyl ester (1), 3-(Z)-caffeoyllupeol, together with five known triterpenoids, lupeol caffeate (2), 3-(Z)-coumaroyllupeol (3), dioslupecin A (4), lupeol (5), and lupenone (6), were isolated from the fruits of Bruguiera parviflora. Their structures were elucidated by spectroscopic methods. Compound 1 exhibited antimalarial activity with an EC50 value of 8.6 mug/ml, but compound 2 was inactive.