Synthesis of 3,4-dihydropyrimidine-2(1H)-thiones and quinazolin-4(3H)-ones over Yb(III)-resin catalyst under solvent-free conditions

Ytterbium(III) reagent supported on ion exchange resin is applied to the multicomponent condensation reactions under solvent-free conditions. One-pot synthesis of a library of 3,4-dihydropyrimidine-2(1H)-thiones and quinazolin-4(3H)-ones were described. The advantages of easy separation and recyclability of the catalysts were demonstrated.