Organic reactions in ionic liquids: Ionic liquid-accelerated one-pot synthesis of 2-arylimidazo[1,2-a]pyrimidines

The room-temperature ionic liquid n-butylpyridinium tetrafluoroborate (BPyBF4) is used as a recyclable alternative to classical molecular solvents in the one-pot synthesis of 2-arylimidazo[1,2-a] pyrimidines by reaction with ketones, [hydroxy(tosyloxy) iodo] benzene, and 2-aminopyrimidine. Significant rate enhancements and improved yields have been observed.