Journal
ARKIVOC
Volume -, Issue -, Pages 9-17Publisher
ARKAT USA INC
DOI: 10.3998/ark.5550190.0006.a02
Keywords
2,7-disubstituted pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines; bis-heterocyclization; carboxylic acids hydrazides
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Derivatives of a new heterocyclic system, viz. pyrazolo[4,3-e][1,2,4] triazolo[1,5-c] pyrimidine 5, have been synthesized by coupling imidoesters of 1-substituted-5-aminocarbonitriles 2 with acylhydrazides. The thermal recyclization of 1-substituted-4-(2-acylhydrazin-1-yl) pyrazolo[3,4d]-pyrimidines 7 is found to be an alternative approach to the heterocyclic system 5.
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