4.8 Article

A green and facile route to gamma- and delta-lactones via efficient Pinner-cyclization of hydroxynitriles in water

Journal

GREEN CHEMISTRY
Volume 8, Issue 1, Pages 22-24

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b513656c

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In the presence of a recyclable cationic exchange resin hydroxynitriles smoothly undergo a Pinner cyclization/hydrolysis two-step reaction in pure water to give lactones in good to excellent yields.

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