Journal
CYTOGENETIC AND GENOME RESEARCH
Volume 115, Issue 1, Pages 7-9Publisher
KARGER
DOI: 10.1159/000094794
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Sheep (OAR), goat (CHI) and cattle (BTA) R-banded chromosome preparations, obtained from synchronized cell cultures, were used to FISH-map leptin (LEP) and solute carrier family 26 member 2 (SLC26A2) genes on single chromosome bands. LEP maps on OAR4q32 and CH14q32, being the first assignment of this gene to these two species. SLC26A2 maps on BTA7q24, OAR5q24 and CH17q24. This gene, too, was assigned for the fist time to both sheep and goat chromosomes, while it was more precisely localized on a single chromosome band in cattle. Improved cytogenetic maps of BTA4/OAR4/CH14 were constructed and compared with HSA7 revealing five main conserved segments and complex chromosome rearrangements, including a centromere repositioning, differentiating HSA7 and BTA4/OAR4/CH14.
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