4.5 Article

UniPep - a database for human N-linked glycosites: a resource for biomarker discovery

Journal

GENOME BIOLOGY
Volume 7, Issue 8, Pages -

Publisher

BMC
DOI: 10.1186/gb-2006-7-8-r73

Keywords

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Funding

  1. NCI NIH HHS [R21 CA114852, U01-CA-111244, U01 CA111244, R21-CA-114852] Funding Source: Medline
  2. NCRR NIH HHS [P41 RR018522, RR18522] Funding Source: Medline
  3. NHLBI NIH HHS [N01-HV-28179, N01HV28179] Funding Source: Medline
  4. DIVISION OF HEART AND VASCULAR DISEASES [N01HV028179] Funding Source: NIH RePORTER
  5. NATIONAL CANCER INSTITUTE [R21CA114852, U01CA111244] Funding Source: NIH RePORTER
  6. NATIONAL CENTER FOR RESEARCH RESOURCES [P41RR018522] Funding Source: NIH RePORTER

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There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N- linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep http://www.unipep.org-a database of human N-linked glycosites - as a resource for biomarker discovery.

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