4.2 Review

Association, commissural, and projection pathways and their functional deficit reported in literature

Journal

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
Volume 30, Issue 5, Pages 695-715

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.rct.0000226397.43235.8b

Keywords

association pathways; commissural pathways; projection pathways; AC; anterior commissure; ACC; anterior cingulate cortex; ACG; anterior cingulum; ALIC; anterior limb of the internal capsule; AR; acoustic radiation; CBT; corticobulbar tract; CC; corpus callosum; CG; cingulum; CST; corticospinal tract; DTI; diffusion tensor imaging; FPT; frontopontine tract; fMRI; functional magnetic resonance imaging; HC; hippocampal (forniceal) commissure; IFOF; inferior fronto-occipital fasciculus; ILF; inferior longitudinal fasciculus; LGN; lateral geniculate nucleus; MGN; medial geniculate nucleus; OR; optic radiation; PC; posterior commissure; PCG; posterior cingulum; PFC; prefrontal cortex; PLIC; posterior limb of the internal capsule; SC; superior colliculi; SFOF; superior fronto-occipital fasciculus; SLF; superior longitudinal fasciculus; TPOPT; temporo-parieto-occipito-pontine tract; TTG; transverse temporal gyrus; TC; tectal commissure; UF; uncinate fasciculus; WM; white matter

Funding

  1. NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS [R01DC005375] Funding Source: NIH RePORTER
  2. NIDCD NIH HHS [R01 DC005375] Funding Source: Medline

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This study demonstrates normal white matter structures of the supratentorial system revealed by diffusion tensor imaging. Their anatomic connections and functional significance are discussed in the context of the lesion-induced deficits reported in the literature, which may not fully represent the lesion-induced effects on the white matter function and may not be entirely specific to the tract discussed. Nevertheless, understanding the most common effects of lesions on the functional connectivity provides a framework that we can use in advanced neuroimaging studies, like diffusion tensor imaging, functional magnetic resonance imaging, and positron emission tomography, and in our daily clinical practice.

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