Journal
EUROPEAN JOURNAL OF HAEMATOLOGY
Volume 76, Issue 6, Pages 531-534Publisher
WILEY
DOI: 10.1111/j.1600-0609.2006.00646.x
Keywords
hepatosplenic gamma-delta T-cell lymphoma; transient response to Fludarabine and Alemtuzumab
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Hepatosplenic gamma-delta T-cell lymphoma is a rare, usually fatal lymphoma and available literature on management is sparse. Allografting is probably the only curative option. We describe a further case with a dramatic, though transient response to Fludarabine and Alemtuzumab combination, following a failure of conventional chemotherapy. Given the dreadful prognosis with conventional chemotherapy, it is a regimen worth pursuing as a disease reduction strategy prior to allograft where appropriate.
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