Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 10, Issue 1, Pages 33-35Publisher
AMER CHEMICAL SOC
DOI: 10.1021/op049779d
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The magnesium salt of (S)-isomer of omeprazole, with a trade name of Nexium, is the first proton-pump inhibitor developed as a single isomer for the treatment of acid-related diseases. A process for the preparation of the optically pure (S)-isomer of omeprazole through transition metal complex is described.
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