Journal
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
Volume 19, Issue 9, Pages 521-528Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14767050600797749
Keywords
pregnancy; periodontal disease; preterm birth; intrauterine growth restriction
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Periodontal disease is a common infectious disease in women of reproductive age. The disease is often not diagnosed and in studies of over 10 000 women has been associated with preterm birth, small for gestational age newborns, and preeclampsia. It has been shown in a smaller number of women that treatment of periodontal disease may reduce the rate of preterm birth. The pregnancy complications of periodontal disease may be due to lipopolysaccharide from the periodontal pockets inciting prostaglandin pathways controlling parturition. Three large randomized controlled trials of treatment of periodontal disease are underway and may provide confirmation of the importance of periodontal disease in causing complications of pregnancy.
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