Journal
AMERICAN JOURNAL ON ADDICTIONS
Volume 15, Issue 1, Pages 8-14Publisher
WILEY
DOI: 10.1080/10550490500418997
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Funding
- NIDA NIH HHS [R0-1 DA03018] Funding Source: Medline
- NATIONAL INSTITUTE ON DRUG ABUSE [Z01DA000241, R01DA003018, Z01DA000413] Funding Source: NIH RePORTER
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This study investigates the clinical significance of a cannabis withdrawal syndrome in 104 adult, nontreatment-seeking, primarily cannabis users who reported at least one serious attempt to stop using cannabis. Retrospective self-report data were obtained on eighteen potential cannabis withdrawal symptoms derived from the literature, including co-occurrence, time course, and any actions taken to relieve the symptom. Study findings provide evidence for the clinical significance of a cannabis withdrawal syndrome, based on the high prevalence and co-occurrence of multiple symptoms that follow a consistent time course and that prompt action by the subjects to obtain relief, including serving as negative reinforcement for cannabis use.
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