Journal
AMERICAN JOURNAL OF PHARMACEUTICAL EDUCATION
Volume 70, Issue 5, Pages -Publisher
AMER ASSOC COLL PHARMACY
DOI: 10.5688/aj700598
Keywords
ergot; ergotism; ergot alkaloids; ergot alkaloid derivatives
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This manuscript reviews the history and pharmacognosy of ergot, and describes the isolation/preparation, chemistry, pharmacodynamics, and pharmacotherapeutics of the major ergot alkaloids and their derivatives. A brief discussion of the hallucinogenic properties of lysergic acid diethylamide is also featured. An abbreviated form of the material found in this paper is presented in a 4-hour didactic format to third-professional year PharmD students as part of their study of vascular migraine headaches, Parkinson's disease, and naturally occurring hallucinogens/hallucinogen derivatives in the modular course offering Neurology/Psychiatry.
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