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Combinatorial discovery of fluorophores and fluorescent probes

Journal

CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 10, Issue 3, Pages 238-245

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.cbpa.2006.04.025

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The properties of organic fluorophores are difficult to predict, even in simple cases. Fluorescent probes - which combine fluorescent properties with the equally challenging problem of molecular recognition - are even more difficult to develop. Combinatorial approaches to the development of such molecules are a new but promising endeavor, and reviewing the state of the art delineates the near-and long-term possibilities.

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