Journal
CHEMICAL SOCIETY REVIEWS
Volume 35, Issue 11, Pages 1095-1104Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b600913c
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This tutorial review presents an overview of strategies for the synthesis and fabrication of organic nanomaterials, specifically those with potential for use in medical applications. Examples include liposomes, micelles, polymer-drug conjugates and dendrimers. Methods of driving shape via bottom-up synthetic approaches and thermodynamics and kinetics are discussed. Furthermore, methods of driving shape via top-down physical and engineering techniques are also explored. Finally, a novel method ( referred to as PRINT) used to produce nanoparticles that are shape-specific, can contain any cargo, and can be easily modified is examined along with its potential future role in nanomedicine.
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