Journal
APPETITE
Volume 46, Issue 1, Pages 31-35Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.appet.2005.09.002
Keywords
binge eating disorder; brain imaging; magnetic resonance imaging; obesity; psychological scales
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Funding
- NIDDK NIH HHS [R03 DK068603-01A2, R03 DK068603, R03 DK068603-02] Funding Source: Medline
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R03DK068603] Funding Source: NIH RePORTER
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Functional neuroimaging was employed to study 10 obese and 10 lean healthy young right-handed women, divided equally into binge and non-binge eaters. Subjects were presented with visual and auditory stimuli of binge type foods, non-binge type foods, and non-food stimuli in the fMRI scanner. Brain areas activated by both the visual and auditory stimuli across all individual subjects within a particular group was observed only for the binge food stimuli in the obese binge eaters, in the right premotor area, involved in planning of motor behavior. For four of the five obese binge eaters, the activation was in the ventral premotor cortex adjacent to the oral region, and may reflect past or concurrent motor planning about eating binge foods. Because a random effects group analysis has not yet been completed, this should be considered a preliminary report. (c) 2005 Elsevier Ltd. All rights reserved.
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