Journal
PHARMACEUTICAL BIOLOGY
Volume 44, Issue 1, Pages 10-13Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/13880200500509025
Keywords
alloxan-induced diabetic rats; beans; Cyamopsis tetragonoloba; hypoglycemic activity; leguminosae
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The effect of administering an ethanol extract of Cyamopsis tetragonoloba Linn. (Leguminosae) beans on blood glucose levels in normal and alloxan-induced diabetic rats was evaluated in this study. The ethanol extract of beans at 250 mg/kg body weight significantly reduced the blood glucose levels in alloxan-induced diabetic rats within 3 h of administration. Continued administration of the extract at the same dose daily for 10 days produced a statistically significant reduction in the blood glucose levels, whereas marginal activity was seen in normal and glucose-loaded rats.
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