Journal
ACTA HISTOCHEMICA
Volume 108, Issue 3, Pages 209-213Publisher
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.acthis.2006.03.011
Keywords
subcutaneous fat; subcutis; biopsy; diagnosis; amyloidosis
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The systemic amyloidoses comprise a biochemically heterogeneous group of potentially lethal disorders. An early and precise diagnosis is crucial for the treatment and prognosis. Subcutaneous fat biopsy is a simple and safe method to obtain a diagnosis of systemic amyloidosis and the material can be used for exact determination of amyloid type. A method is described for immunochemical typing of the amyloid based on Western blot analysis combined with specific amyloid fibril protein antibodies. (C) 2006 Elsevier GmbH. All rights reserved.
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