Journal
SCIENCE IN CHINA SERIES G-PHYSICS MECHANICS & ASTRONOMY
Volume 49, Issue 3, Pages 304-312Publisher
SCIENCE PRESS
DOI: 10.1007/s11433-006-0304-z
Keywords
cell coupling; collective response; system size resonance
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By the intracellular calcium ionic minimal model proposed by Berridge, we investigated the collective response of two-dimensional (NxN) coupled cell systems to the external stimulation using numerical simulation methods. With a coupled intensity fixed and an appropriate coupled cell number chosen, the kinetic system size resonance was discovered. At the same time, it was found that the system size responding to the external stimulation for different coupled intensities transferred too, especially when the coupled intensity increased, the range of the corresponding system size extended. These phenomena illustrate that the coupled cell number and the coupled intensity can play constructive roles in noisy coupled systems, by which the biology system would probably improve its capability to respond to the external stimulation.
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