Journal
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
Volume 8, Issue 5, Pages 717-722Publisher
BMC
DOI: 10.1080/10976640600723839
Keywords
shear stress; carotid artery disease; phase contrast; velocity; magnetic resonance angiography
Funding
- NHLBI NIH HHS [R01 HL59345] Funding Source: Medline
- NINDS NIH HHS [R01 NS30928] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL059345] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R01NS030928] Funding Source: NIH RePORTER
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In this study we determined mean-average wall shear stress values in the common carotid artery and assessed if there is a difference in mean-average WSS between: 1) patients with bilateral carotid bifurcation disease and 2) similar-aged volunteers with no evidence of disease. Sixteen patients with bilateral disease of the carotid bifurcation, and 8 volunteers were included in the study. Magnetic resonance phase velocity mapping was used to determine velocity, flow, vessel cross-sectional dimensions, and mean-average WSS in the common carotid artery in both the patients and volunteers. Mean-average WSS in the common carotid artery was 7.5 +/- 2.5 dynes/cm(2) in patients and 8.0 +/- 4.1 dynes/cm(2) in volunteers. There was no significant difference in mean-average WSS , average velocity, peak velocity, flowrate, or vessel diameter in the common carotid artery between patients and volunteers.
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