4.4 Review

Interactions between Purkinje neurones and bergmann glia

Journal

CEREBELLUM
Volume 5, Issue 2, Pages 116-126

Publisher

SPRINGER
DOI: 10.1080/14734220600724569

Keywords

Bergmann glial cell; Purkinje neurone; parallel fibre; climbing fibre; synaptic plasticity

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Funding

  1. Biotechnology and Biological Sciences Research Council [BB/B500958/1] Funding Source: Medline

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Throughout the development of the cerebellar cortex, Purkinje neurones interact closely with Bergmann glial cells, a specialized form of astrocyte. This review summarizes the intimate developmental, anatomical and functional relationships between these two cell types, with particular emphasis on recent discoveries regarding glutamate release from climbing and parallel fibres as a pathway for signalling synaptic activity to Bergmann glia.

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