Journal
MICROBIOLOGICAL RESEARCH
Volume 161, Issue 2, Pages 180-186Publisher
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.micres.2005.08.005
Keywords
cyanobacteria; exometabolites; antimicrobial activity; allelopathy; antifouling agents
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The antimicrobial activity of two cyanobacterial exometabolites, norharmane (9H-pyrido(3,4-b)indole) and 4,4'-dihydroxybiphenyl, was determined in suspension assays. Good anticyanobacterial activities (concentrations of 8-80 mu g ml(1)) and moderate antibacterial (16-160 mu g ml (1)) and antifungal (32 40 mu g ml(1)) activities were found for both compounds. The natural function as alletopathic chemicals and a possible applicability as antifouling agents or leads for the development of new antifouling chemicals are discussed. (C) 2005 Elsevier GmbH. All rights reserved.
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