Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 16, Issue 1, Pages 96-99Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.09.042
Keywords
thienopyrazoles; kinase inhibitors; KDR inhibitors; targeted libraries; de novo design
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We report the synthesis of kinase targeted libraries based on the thienopyrazole scaffold. Several thienopyrazole analogs have been identified as submicromolar inhibitors of KDR. (c) 2005 Elsevier Ltd. All rights reserved.
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