Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 47, Pages 4928-4930Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b611366d
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Optically active 2,5-disubstituted-cyclohexen-2-one derivatives have been prepared in a one-pot process consisting of five reaction steps: an organocatalytic asymmetric conjugated addition of beta-ketoesters to alpha,beta-unsaturated aldehydes that proceeds in aqueous solutions or under solvent-free conditions has been implemented in a multi-step process.
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