Journal
NUCLEIC ACIDS RESEARCH
Volume 34, Issue -, Pages D489-D494Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkj114
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Funding
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM067761, R01GM078176] Funding Source: NIH RePORTER
- NIGMS NIH HHS [R01 GM078176, R01 GM067761] Funding Source: Medline
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RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library of over 21 000 double-stranded RNAs targeting known and predicted genes in Drosophila. This library is available for the use of visiting scientists wishing to perform full-genome RNAi screens. The data generated from these screens are collected in the DRSC database (http://flyRNAi.org/cgi-bin/RNAi_screens.pl) in a flexible format for the convenience of the scientist and for archiving data. The long-term goal of this database is to provide annotations for as many of the uncharacterized genes in Drosophila as possible. Data from published screens are available to the public through a highly configurable interface that allows detailed examination of the data and provides access to a number of other databases and bioinformatics tools.
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