4.7 Article

Tetramethylpyridiniumporphyrazines - a new class of G-quadruplex inducing and stabilising ligands

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 45, Pages 4685-4687

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b611731g

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Funding

  1. Cancer Research UK [A5709] Funding Source: Medline

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3,4-Tetramethylpyridiniumporphyrazines bind strongly and selectively to human telomeric G-quadruplex DNA, inducing the formation of an antiparallel quadruplex in a process that mimics molecular chaperones.

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