Enantioselective rhodium-catalyzed addition of arylboronic acids to trifluoromethyl ketones

The catalytic asymmetric 1,2-addition of a series of arylboronic acids to 2,2,2-trifluoroacetophenones is described with high isolated yields ( up to 96%) and good enantioselectivities ( up to 83% ee) using a rhodium( I)/phosphoramidite catalyst.