4.7 Article

Phosphonopeptide K-26 biosynthetic intermediates in Astrosporangium hypotensionis

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 43, Pages 4518-4520

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b611768f

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Funding

  1. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM077189] Funding Source: NIH RePORTER
  2. NIGMS NIH HHS [R01GM077189-01] Funding Source: Medline

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Precursors and advanced intermediates for phosphonopeptide K-26 biosynthesis were synthesized and incorporation studies in Astrosporangium hypotensionis suggest a new mechanism of C - P bond formation in aromatic phosphonates.

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