4.7 Article

Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 48, Pages 5003-5005

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b611650g

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Funding

  1. Engineering and Physical Sciences Research Council [GR/S07438/01] Funding Source: researchfish

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A novel anthracene-tagged oligonucleotide can discriminate between a fully-matched DNA target sequence and one with a single mismatching base-pair through a remarkable difference in fluorescence emission intensity upon duplex formation.

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