4.7 Article

A new consecutive three-component oxazole synthesis by an amidation-coupling-cycloisomerization (ACCI) sequence

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 46, Pages 4817-4819

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b610839c

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A novel consecutive three-component synthesis of 1-(hetero)aryl- 2-(2-(hetero)aryl-oxazol-5-yl) ethanones starting from propargyl amine and acid chlorides, both for amidation and cross-coupling, is based upon an amidation-coupling-cycloisomerization (ACCI) sequence.

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