4.5 Article

Dendritic architecture of the von Economo neurons

Journal

NEUROSCIENCE
Volume 141, Issue 3, Pages 1107-1112

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neuroscience.2006.04.084

Keywords

spindle cell; anterior cingulate; fronto-insula; Golgi; human brain; ape

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Funding

  1. NICHD NIH HHS [N01-HD-4-3368] Funding Source: Medline

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The von Economo neurons are one of the few known specializations to hominoid cortical microcircuitry. Here, using a Golgi preparation of a human postmortem brain, we describe the dendritic architecture of this unique population of neurons. We have found that, in contrast to layer 5 pyramidal neurons, the von Economo neurons have sparse dendritic trees and symmetric apical and basal components. This result provides the first detailed anatomical description of a neuron type unique to great apes and humans. (c) 2006 Published by Elsevier Ltd on behalf of IBRO.

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