Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 50, Issue 6, Pages 2228-2230Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01620-05
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The mutant prevention concentrations (MPCs) of levofloxacin alone and in combination with ceftazidime, colistin (polymyxin E), meropenem, piperacillin-tazobactam, and tobramycin were established against Pseudomonas aeruginosa. Antibiotic combinations using levofloxacin with any antibiotic with individual activity against P. aeruginosa resulted in synergistic lowering (an at-least-fourfold reduction) of the isolate's MPC.
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