Journal
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
Volume 12, Issue 1, Pages 107-112Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.bbmt.2005.09.005
Keywords
regression model; hazard rates; cumulative incidence probabilities; hematopoietic cell transplantation
Categories
Ask authors/readers for more resources
In this article, we consider methods of regression modeling in the competing risks setting commonly encountered in analyzing stem cell transplantation data. We clarify the distinction between modeling the cause-specific hazard rate and modeling the cumulative incidence probability or function, and we review regression techniques for both types of quantities. We apply them to 2 examples: 1 comparing engraftment and I examining relapse. These examples illustrate that different conclusions may result depending on the type of regression model used for comparing treatments. Finally, we show how these discrepancies occur because 2 different characteristics of the time-to-event distribution are being modeled. (C) 2006 American Society for Blood and Marrow Transplantation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available