Journal
GENETICS
Volume 172, Issue 1, Pages 713-718Publisher
GENETICS
DOI: 10.1534/genetics.105.044065
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Funding
- NIGMS NIH HHS [GM072861, R01 GM072861] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM072861] Funding Source: NIH RePORTER
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Most models of positive directional selection assume codominance of the beneficial allele. We examine the importance of this assumption by implementing a coalescent model of positive directional selection with arbitrary dominance. We find that, for a given mean fixation time, a beneficial allele has a much weaker effect on diversity at linked neutral sites when the allele is recessive.
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