Journal
NANO LETTERS
Volume 6, Issue 1, Pages 29-33Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nl051804l
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- Engineering and Physical Sciences Research Council [EP/C523857/1, GR/R60614/01] Funding Source: researchfish
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We demonstrate the fabrication of sub-100-nm DNA surface patterns by scanning near-field optical lithography using a near-field scanning optical microscope coupled to a UV laser and a chloromethylphenylsiloxane (CMPS) self-assembled monolayer (SAM). The process involves 244-nm exposure of the CMPS SAM to create nanoscale patterns of surface carboxylic acid functional groups, followed by their conversion to the N-hydroxysuccinimidyl ester and reaction of the active ester with DNA to spatially control DNA grafting with high selectivity.
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