Journal
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
Volume 16, Issue -, Pages 273-277Publisher
BMJ PUBLISHING GROUP
DOI: 10.1111/j.1525-1438.2006.00416.x
Keywords
serous; NACT; intervaldebulking; endometrial
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Serous endometrial carcinoma (SEC) is an uncommon variant of endometrial carcinoma that is notorious for its aggressive clinical course. Similar to its ovarian counterpart, it has a propensity for early intra-abdominal and lymphatic spread. We present two cases of advanced SEC, who were left with no residual tumor after neoadjuvant chemotherapy. After three courses of chemotherapy, both patients underwent interval debulking surgery, resulting in no residual disease. The documentation of chemosensitivity might enable the clinician to select a subpopulation of patients with widespread SEC that might benefit from interval debulking surgery.
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