Journal
NATURE BIOTECHNOLOGY
Volume 24, Issue 1, Pages 76-77Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nbt1170
Keywords
-
Categories
Ask authors/readers for more resources
Little is known about the potential of plastids to accomplish post-translational modifications of foreign proteins. In the present study we generated transplastomic tobacco plants that accumulate the outer surface lipoprotein A (OspA) - the basic constituent of the first generation monovalent human vaccine against Lyme disease. The recombinant OspA exhibits a lipid modification typical for bacteria and induced protective antibodies in mice, demonstrating that functionally active bacterial lipoproteins can be processed in plants.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available