4.3 Article

Convergent one-pot synthesis of 3-substituted quinazolin-4(3H)-ones under solvent-free conditions

Journal

SYNTHETIC COMMUNICATIONS
Volume 36, Issue 15, Pages 2245-2252

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910600639257

Keywords

formic acid; isatoic anhydride; microwave; quinazolin-4(3H)-one; solvent-free

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A convenient method for the synthesis of 3-substituted quinazolin-4(3H)-ones using the convergent reactions of formic acid, a primary amine, and isatoic anhydride under solvent-free conditions and with brief microwave irradiation is described.

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