4.3 Article

1,1,3,3-N,N,N ',N '-tetramethylguanidinium trifluoroacetate ionic liquid-promoted efficient one-pot synthesis of trisubstituted imidazoles

Journal

SYNTHETIC COMMUNICATIONS
Volume 36, Issue 1, Pages 65-70

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910500328969

Keywords

imidazole; ionic liquid; one-pot condensation reaction; 1,1,3,3-N,N,N ',N '-tetramethylguanidinium trifluoroacetate

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Trisubstituted imidazoles have been synthesized in very short reaction times with excellent yields in the presence of 1,1,3,3- N , N , N ', N '-tetramethylguanidinium trifluoroacetate as an ionic liquid at 100 degrees C. The ionic liquid can be recycled for subsequent reactions without any appreciable loss of efficiency.

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