Journal
EUROPEAN UROLOGY
Volume 49, Issue 1, Pages 22-29Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.eururo.2005.10.004
Keywords
neurogenic; spinal cord injury; spina bifida; bladder reinnervation; neurosurgical procedure
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Funding
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK053063, R01DK044877] Funding Source: NIH RePORTER
- NIDDK NIH HHS [R01 DK44877, R01 DK53063] Funding Source: Medline
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Neurogenic bladder caused by SCI or spina bifida is a major problem. Research in restoring functional micturition has mainly focused on electrical stimulation for many decades with good progress, but it is still not the definitive solution for majority of the SCI patients. An alternative approach has been to investigate restoring innervation to the lower urinary tract after spinal SCI. Different animal and clinical studies were reviewed historically in this article, focused on mainly cross over nerve surgery for reinnervation of the bladder. An artificial somatic-autonomic reflex pathway procedure and its mechanisms were introduced. Clinical application and the satisfactory results of the new procedure were reviewed in details in restoring voluntary bladder control in patients with SCI or spina bifida. (c) 2005 Elsevier B.V. All rights reserved.
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