4.7 Article

Phaeofurans and sorbicillin analogues from a fungicolous Phaeoacremonium species (NRRL 32148)

Journal

JOURNAL OF NATURAL PRODUCTS
Volume 69, Issue 1, Pages 113-117

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/np0504199

Keywords

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Funding

  1. NIGMS NIH HHS [R01 GM060600-07, R01 GM060600-04, R01 GM060600-05, R01 GM060600-06, R01 GM 60600, R01 GM060600] Funding Source: Medline
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM060600] Funding Source: NIH RePORTER

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Two new benzofuran-derived metabolites of polyketide origin called phaeofurans A and B (1 and 2), along with three sorbicillin analogues (3-5), have been obtained from a fungicolous isolate of the genus Phaeoacremonium (NRRL 32148). The structures were determined by analysis of MS and 2D NMR data. The antifungal effects of the extract were ascribed to the sorbicillin analogues.

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