Vitellogenin gene expression as a biomarker of endocrine disruption in the invertebrate, Mytilus edulis

Vitellogenin levels are often used as a biomarker of endocrine disruption in fish. For invertebrates, there is a general lack of knowledge regarding endocrine regulation and, consequently, there are few direct biomarkers of endocrine disruption in such species. This study focuses on the marine mussel Mytilus edulis, which is often employed in biomonitoring studies. A partial vitellogenin mRNA has been isolated and gene expression quantified using real-time PCR. (c) 2006 Elsevier Ltd. All rights reserved.