Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 54, Issue 1, Pages 4-8Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.54.4
Keywords
marine sponge; Jaspis sp.; isomalabaricanes; terpenoids; structural elucidation
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A chemical investigation of Jaspis sp., the marine sponge collected from the South China Sea led to the isolation of six new isomalabaricane-type compounds, jaspolides A-F (1-6). The structures of those compounds were elucidated by extensive spectroscopic methods. The structure-types of 1 to 6 could be classified into triter-penes (1, 2), sesterterpene (6), diterpenes (3, 4), and nortriterpene (5). The biogenetic transformation of the isolated compounds was also speculated.
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