Journal
JOURNAL OF BIOMECHANICS
Volume 39, Issue 8, Pages 1557-1561Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2005.04.020
Keywords
biological tissues; mitral valve; large strain; constitutive models; finite element formulation
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This paper presents a finite element formulation suitable for large-strain modeling of biological tissues and uses this formulation to implement an accurate finite element model for mitral valve leaflet tissue. First, an experimentally derived strain energy function is obtained from literature. This function is implemented in finite elements using the mixed pressure-displacement formulation. A modification is made to aid in maintaining positive definiteness of the stiffness matrix at low strains. The numerical implementation is shown to be accurate in representing the analytical model of material behavior. The mixed formulation is useful for modeling of soft biological tissues in general, and the model presented here is applicable to finite element simulation of mitral valve mechanics. (c) 2005 Elsevier Ltd. All rights reserved.
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