Journal
NATURE NEUROSCIENCE
Volume 9, Issue 1, Pages 23-25Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nn1616
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Funding
- NINDS NIH HHS [NS06833] Funding Source: Medline
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P01NS006833, P50NS006833] Funding Source: NIH RePORTER
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Trial-to-trial variability in the blood oxygen level-dependent (BOLD) response of functional magnetic resonance imaging has been shown to be relevant to human perception and behavior, but the sources of this variability remain unknown. We demonstrate that coherent spontaneous fluctuations in human brain activity account for a significant fraction of the variability in measured event-related BOLD responses and that spontaneous and task-related activity are linearly superimposed in the human brain.
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