Journal
INTERNAL MEDICINE
Volume 45, Issue 16, Pages 975-980Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.45.1699
Keywords
disseminated adenovirus disease; fulminant hepatic failure; bone marrow transplantation; leukemia
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Adenovirus is one of the major causes of non-relapse morbidity and mortality after allogeneic hematopoietic stem cell transplantation for hematological malignancy. Fulminant hepatic failure is a rare manifestation of post-transplant complication with adenovirus. Extremely high mortality and aggressiveness of the clinical course have been posing clinical challenges for the diagnosis as well as for the treatment. Here, we report a case with disseminated adenovirus disease presenting with fulminant hepatic failure after bone marrow transplantation for acute lymphoblastic leukemia.
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